HACL1 Antibody

中文名稱：

HACL1兔多克隆抗體
貨號(hào)：

CSB-PA546627
規(guī)格：

￥1100
圖片：
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Human testis tissue, mouse liver tissue, Hela cells, 293T cells, Primary antibody: CSB-PA546627(HACL1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
其他：

產(chǎn)品詳情

Uniprot No.：

Q9UJ83
基因名：

HACL1
別名：

1600020H07Rik antibody; 2 HPCL antibody; 2 hydroxyacyl CoA lyase 1 antibody; 2 hydroxyphytanoyl CoA lyase antibody; 2-HPCL antibody; 2-hydroxyacyl-CoA lyase 1 antibody; 2-hydroxyphytanoyl-CoA lyase antibody; FLJ55041 antibody; Hacl1 antibody; HACL1_HUMAN antibody; HPCL antibody; HPCL2 antibody; HSPC279 antibody; PHYH2 antibody; Phytanoyl CoA 2 hydroxylase 2 antibody; Phytanoyl CoA hydroxylase 2 antibody; Phytanoyl-CoA 2-hydroxylase 2 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Fusion protein of Human HACL1
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

Antigen affinity purification
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB

推薦稀釋比：

Application	Recommended Dilution
ELISA	1:1000-1:2000
WB	1:200-1:1000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Peroxisomal 2-OH acyl-CoA lyase involved in the cleavage (C1 removal) reaction in the fatty acid alpha-oxydation in a thiamine pyrophosphate (TPP)-dependent manner. Involved in the degradation of 3-methyl-branched fatty acids like phytanic acid and the shortening of 2-hydroxy long-chain fatty acids. Plays a significant role in the biosynthesis of heptadecanal in the liver.
基因功能參考文獻(xiàn)：
1. Data show that a easy assay for 2-hydroxyacyl-CoA lyase (HACL1) and sphingosine-1-phosphate lyase (SGPL1) activities was developed. PMID: 24323699
2. Transport of thiamine pyrophosphate into peroxisomes is dependent on HACL1 import, without requirement of a specific solute transporter. PMID: 21708296
3. 2-hydroxyphytanoyl-CoA lyase has a role in the breakdown of long chain 2-hydroxyfatty acids PMID: 15644336
4. peroxisomal thiamine-pyrophosphate depending enzyme required for the degradation of phytanic acid, catalyzing the cleavage of 2-hydroxyphytanoyl-CoA lyase into formyl-CoA and pristanal PMID: 10468558
亞細(xì)胞定位：

Peroxisome.
蛋白家族：

TPP enzyme family
組織特異性：

Widely expressed.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 17856

OMIM: 604300

KEGG: hsa:26061

STRING: 9606.ENSP00000323811

UniGene: Hs.63290

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