Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
基因功能參考文獻:
the GSTA2 S112T polymorphism is predictive of transplant outcome in patients receiving busulfan in the preparative regimen, at least in association with cyclophosphamide. PMID: 24056816
Single nucleotide polymorphism in GSTA2 is associated with low-stage non-small cell lung cancer. PMID: 21792076
it is unlikely that glutathione S-transferases GSTA2, GSTM2, GSTO1, GSTO2, and GSTZ1 participate in breast cancer susceptibility. PMID: 19859803
studied the five known allelic variants of human glutathione transferase A2-2 (GST A2-2) (EC 2.5.1.18), abundantly expressed in liver and efficiently catalyzing the bioactivation of azathioprine to release 6-mercaptopurine PMID: 20434437
The 3D structures of human GSTs A2-2 and A3-3 in complex with Delta(4)-androstene-3-17-dione, were solved. PMID: 20083122
Polymorphism identified in the proximal promoter of GSTA2 correlate with its expression in the liver and is expected to be of significance for individual risk of cancer or individual response to chemotherapeutic agents. PMID: 11692074
transmutation into an efficient steroid isomerase PMID: 12023294
no association was observed between individual GSTA2 polymorphisms and haplotypes and individual susceptibility to breast cancer. PMID: 19639209
Overexpression of GSTA2 by transient transfection protected Colo 320HSR cells against both cycle arrest and apoptosis following exposure to HN2. PMID: 15778998