GINS3 Antibody
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中文名稱：GINS3兔多克隆抗體
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貨號：CSB-PA009432GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：GINS3
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別名：DNA replication complex GINS protein PSF3 antibody; GINS complex subunit 3 antibody; Gins3 antibody; PSF3 homolog antibody; PSF3_HUMAN antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human GINS3
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.
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基因功能參考文獻：
- The authors show that GINS is a compact tetramer in solution as observed in crystal structures, but also forms a double-tetrameric population, detectable by electron microscopy. PMID: 28071757
- expression in primary lung adenocarcinoma plays an important role in disease progression and is a prognostic indicator PMID: 27005977
- Psf3 expression was strongly correlated with tumor progression in non-small-cell lung cancer PMID: 26291987
- Two downregulated genes, NDRG4 and GINS3, have been located in a genomic interval associated with cardiac repolarization in published GWASs and zebra fish knockout models PMID: 25520251
- PSF3 expression plays an important role in the progression of colorectal cancer and acts as a factor significantly affecting the prognosis of patients. PMID: 25403684
- a prognostic biomarker in lung adenocarcinoma PMID: 23127337
- These results suggest that PSF3 is a potential biomarker for diagnosis of progression in colon cancer and could PMID: 20059967
- expression of mammalian GINS is regulated by 17beta-Estradiol-stimulated estrogen receptor alpha, and PSF3 acts as a gene responsive to transcription factor E2F1 PMID: 17127213
- This sensitized zebrafish screen identified 15 novel myocardial repolarization genes. Among these genes is GINS3, the human ortholog of which is a major locus in 2 concurrent human genome-wide association studies of QT interval. PMID: 19652097
- This paper describes work done in Saccharomyces cerevisiae. PMID: 12730134
- This paper describes work done in Schizosaccharomyces pombe. PMID: 16990792
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亞細胞定位：Nucleus. Chromosome.
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蛋白家族：GINS3/PSF3 family
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數據庫鏈接：
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