GABPB1 Antibody
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中文名稱(chēng)：GABPB1兔多克隆抗體
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貨號(hào)：CSB-PA009138GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：GABPB1
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別名：BABPB2 antibody; E4TF1 antibody; E4TF1-47 antibody; E4TF1-53 antibody; E4TF1B antibody; GA binding protein transcription factor beta subunit 1 transcript variant gamma 2 antibody; GA binding protein transcription factor, beta subunit 1 antibody; GA binding protein transcription factor, beta subunit 2 antibody; GA-binding protein subunit beta-1 antibody; GABP subunit beta-1 antibody; GABP subunit beta-2 antibody; GABP1_HUMAN antibody; GABPB antibody; GABPB-1 antibody; GABPB-2 antibody; GABPB1 antibody; GABPB2 antibody; NRF2B1 antibody; NRF2B2 antibody; Nuclear respiratory factor 2 antibody; Transcription factor E4TF1-47 antibody; Transcription factor E4TF1-53 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human GABPB1
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a a master regulator of nuclear-encoded mitochondrial genes.; (Microbial infection) Necessary for the expression of the Adenovirus E4 gene.
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基因功能參考文獻(xiàn)：
- Data revealed high expression of GABPB1 in clear cell renal cell carcinoma (ccRCC) tissues and cell lines. Its knockdown significantly decreased the colony formation ability via induction of p21Waf/Cip1 expression. Furthermore, the patients at high risk of a poor survival outcome exhibited the highest expression level of GABPB1. These findings imply that GABPB1 serves an important role in the progression of ccRCC. PMID: 29845229
- Ectopic overexpression of a dominant-negative acting GABP mutant led to impaired myeloid differentiation of CD34(+) hematopoietic stem/progenitor cells. PMID: 27100840
- role for GABPA/B1 as the critical ETS transcription factors deregulating SDHD expression in the context of highly recurrent promoter mutations in melanoma. PMID: 28108517
- GABP beta is required for YAP expression in vitro and in vivo, and that YAP is an important effector downstream of GABP for cell survival and cell-cycle progression. PMID: 23684612
- The NRF-2beta nuclear localization signal (NLS) is an unusual but is, nevertheless, a bona fide monopartite-type NLS. PMID: 23856623
- NRF-1 and GABP expression is coordinated by NRF-1's activation of the GABPbeta promoter PMID: 21609478
- Data show that BRAF knockdown led to suppression of the expression of the GABPbeta, which involved in regulating HPR1 promoter activity. PMID: 21076620
- Mutation of a nuclear respiratory factor 2 binding site in the 5' untranslated region of the ADSL gene in three patients with adenylosuccinate lyase deficiency. PMID: 12016589
- Results point out that brain-specific angiogenesis inhibitor 2 controls VEGF transcription through GA-binding protein under normal conditions and cerebral ischemia [GA-binding protein gamma]. PMID: 16412436
- serum-responsive GABP binding to Ets-binding sites activates the KIS promoter, leading to KIS gene expression, cell migration, and cell cycle progression PMID: 17726090
- The results are consistent with a pathway whereby PRC regulates NRF-2-dependent genes through a multiprotein complex involving HCF-1.[NRF-2beta] PMID: 18343819
- The cyrstal structure of a ternary complex containing the mouse GA binding protein transcription factor, beta subunit 2, was resolved at 2.15 angstrom resolution. PMID: 9461436
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亞細(xì)胞定位：Nucleus.
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數(shù)據(jù)庫(kù)鏈接：
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