FANCB Antibody, Biotin conjugated
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中文名稱：FANCB兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA818751LD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) FANCB Polyclonal antibody
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Uniprot No.：
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基因名：FANCB
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別名：FA2 antibody; FAAP90 antibody; FAAP95 antibody; FAB antibody; FACB antibody; Fancb antibody; FANCB_HUMAN antibody; Fanconi anemia associated polypeptide of 95 kDa antibody; Fanconi anemia group B protein antibody; Fanconi anemia; complementation group B antibody; Fanconi anemia-associated polypeptide of 95 kDa antibody; Protein FACB antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Fanconi anemia group B protein (431-574AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：DNA repair protein required for FANCD2 ubiquitination.
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基因功能參考文獻：
- We identified a 9154 bp intragenic duplication in FANCB, covering the first coding exon 3 and the flanking regions. The duplicated allele gives rise to an aberrant transcript containing exon 3 duplication, predicted to introduce a stop codon in FANCB protein (p.A319*). PMID: 29193904
- Four single nucleotide polymorphisms were identified, three of which were located in untranslated regions of Fanconi anemia group B protein (FANCB) and predicted to be associated with normal function. PMID: 29491055
- Loss-of-function FANCB mutations result in a recognizable, multiple malformation phenotype in hemizygous males for which we propose clinical criteria to aid diagnosis. PMID: 21910217
- Inactivation of FancB may play a role in the pathogenesis of sporadic HNSCC. PMID: 20332657
- Elevated serum FA-2 was associated with bony metastases from breast cancer. PMID: 20465790
- the protein defective in individuals with Fanconi anemia belonging to complementation group B is an essential component of the nuclear protein 'core complex' responsible for monoubiquitination of FANCD2 PMID: 15502827
- summary of recent advances in the Fanconi anemia-BRCA network with emphasis on the new discovery of FAAP95 as the true FANCB gene [review] PMID: 15611632
- Mutations in FANCB are a cause of X linked VACTERL-H syndrome. PMID: 16679491
- Mus81 and FANCB have different roles in repair of DNA damage during replication in human cells PMID: 17903171
- Our results rule out a major contribution of FANCB to hereditary breast cancer. PMID: 18302019
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相關疾病：Fanconi anemia complementation group B (FANCB)
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亞細胞定位：Nucleus.
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數據庫鏈接：
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