ERGIC2 Antibody

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) ERGIC2 Polyclonal antibody
Uniprot No.：

Q96RQ1
基因名：

ERGIC2
別名：

ERGIC2; ERV41; PTX1; CDA14; Endoplasmic reticulum-Golgi intermediate compartment protein 2
宿主：

Rabbit
反應種屬：

Human, Mouse
免疫原：

Recombinant Human Endoplasmic reticulum-Golgi intermediate compartment protein 2 protein (55-310AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產品提供形式：

Liquid
應用范圍：

ELISA, WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Possible role in transport between endoplasmic reticulum and Golgi.
基因功能參考文獻：
1. A variant of ERGIC2 with four coding bases deleted has an abrogated function as a transport shuttle, but does continue to upregulate the heme oxygenase 1 gene, suggesting that it may be involved in the oxidative stress pathway. PMID: 24303950
2. may play an important role in the growth and tumorigenicity of PC-3 prostate tumor cells PMID: 12932305
3. ERGIC-32 functions as a modulator of the hErv41-hErv46 complex by stabilizing hErv46 PMID: 15308636
4. Ectopic expression of a partial sequence of PTX1 (Met84 - Leu225) as a VP22-fusion protein in prostate cancer cell line, PC-3, induced cellular senescence. PMID: 16989575
5. CDA14 participated in the elongation factor 1alpha regulated mechanisms PMID: 17980171
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亞細胞定位：

Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasm. Nucleus.
蛋白家族：

ERGIC family
組織特異性：

Ubiquitously expressed.
數據庫鏈接：

HGNC: 30208

OMIM: 612236

KEGG: hsa:51290

STRING: 9606.ENSP00000353270

UniGene: Hs.339453

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