Western Blot
Positive WB detected in: NIH/3T3 whole cell lysate, HepG2 whole cell lysate, Mouse brain tissue, Rat heart tissue
All lanes: EMB antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 37, 32 kDa
Observed band size: 70 kDa
Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA754239LA01HU at dilution of 1:100
Immunofluorescent analysis of A549 cells using CSB-PA754239LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane.
基因功能參考文獻:
Study reports elevated expression of Embigin in pancreatic ductal adenocarcinoma and shows its novel functions in regulating cell proliferation, migration, and invasion. PMID: 25773908
embigin is regulated by HOXC8 and its loss plays an important role in the progression of breast tumors PMID: 26090721
Data show that Gp70 (embigin) was negative in all normal, adjacent non-neoplastic and PIN lesions and only a very small percentage of cases. PMID: 21787388
Reports the original cloning of the mouse embigin gene, referred to as gp70, from embryonal carcinoma cells. PMID: 2963822
亞細胞定位:
Cell membrane; Single-pass type I membrane protein. Cell junction, synapse.