EIF2S2 Antibody
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中文名稱：EIF2S2兔多克隆抗體
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貨號：CSB-PA007524GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：EIF2S2
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別名：DKFZp686L18198 antibody; eIF 2 beta antibody; eIF-2-beta antibody; EIF2 antibody; EIF2B antibody; EIF2beta antibody; EIF2S2 antibody; Eukaryotic initiation factor 2 beta antibody; eukaryotic initiation factor 2-beta antibody; Eukaryotic translation initiation factor 2 beta antibody; Eukaryotic translation initiation factor 2 subunit 2 antibody; Eukaryotic translation initiation factor 2 subunit 2 beta 38kDa antibody; Eukaryotic translation initiation factor 2 subunit 2 beta antibody; Eukaryotic translation initiation factor 2 subunit beta antibody; eukaryotic translation initiation factor 2; subunit 2 beta; 38kDa antibody; IF2B_HUMAN antibody; MGC8508 antibody; PPP1R67 antibody; protein phosphatase 1; regulatory subunit 67 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Human EIF2S2
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IF
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
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基因功能參考文獻：
- Data suggest that eukaryotic translation initiation factor 2 subunit beta (eIF2beta) is a therapeutic target for lung cancer. PMID: 29624814
- This study provides mechanistic insight into the role of eIF5-carboxyl terminal domain's dynamic interplay with eIF1 and eIF2beta PMID: 22813744
- These findings suggest that alpha and beta subunits of eIF2 interact with each other and the beta-subunit plays a critical role both in the regulation and function of eIF2. PMID: 18639529
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蛋白家族：EIF-2-beta/eIF-5 family
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數據庫鏈接：
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