EIF2B3 Antibody

說明書

中文名稱：

EIF2B3兔多克隆抗體
貨號(hào)：

CSB-PA002287
規(guī)格：

￥1090
圖片：
Western Blot analysis of K562 cells using eIF2Bγ Polyclonal Antibody

Western Blot analysis of K562 cells using eIF2Bγ Polyclonal Antibody
其他：

產(chǎn)品詳情

Uniprot No.：

Q9NR50
基因名：

EIF2B3
別名：

EI2BG_HUMAN antibody; EIF 2B antibody; eIF 2B GDP GTP exchange factor subunit gamma antibody; eIF-2B GDP-GTP exchange factor subunit gamma antibody; eIF2B-gamma antibody; Eif2b3 antibody; EIF2Bgamma antibody; Eukaryotic translation initiation factor 2B subunit 3 gamma antibody; Eukaryotic translation initiation factor 2B; gamma antibody; eukaryotic translation initiation factor 2B; subunit 3 gamma; 58kDa antibody; OTTHUMP00000010262 antibody; OTTHUMP00000010263 antibody; Translation initiation factor eIF-2B subunit gamma antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse
免疫原：

Synthesized peptide derived from the Internal region of Human eIF2Bγ.
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:5000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
基因功能參考文獻(xiàn)：
1. To determine the tolerance differences to ERS, cell viability and apoptosis rates were detected in oligodendrocyte cell lines transfected with EIF2B3-c.1037T>C or the wild type. We confirmed that oligodendrocytes with mutant EIF2B3 was less tolerant to ERS than the wild type, with decreased cell viability and increased apoptosis rates. PMID: 26625702
2. Results show significant higher incidence of Chinese patients with EIF2B3 mutations compared with Caucasian patients. The c.1037T>C in EIF2B3 was confirmed to be a founder mutation in Chinese explaining the genotypic differences between ethnicities. PMID: 25761052
相關(guān)疾病：

Leukodystrophy with vanishing white matter (VWM)
蛋白家族：

EIF-2B gamma/epsilon subunits family
數(shù)據(jù)庫鏈接：

HGNC: 3259

OMIM: 603896

KEGG: hsa:8891

STRING: 9606.ENSP00000353575

UniGene: Hs.533549

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