DUSP15 Antibody
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中文名稱：DUSP15兔多克隆抗體
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貨號：CSB-PA007244GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：DUSP15
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別名：bA243J16.5 antibody; Chromosome 20 open reading frame 57 antibody; Dual specificity phosphatase 15 antibody; Dual specificity phosphatase like 15 antibody; Dual specificity protein phosphatase 15 antibody; DUS15_HUMAN antibody; DUSP15 antibody; EC 3.1.3.16 antibody; EC 3.1.3.48 antibody; FLJ20645 antibody; Vaccinia virus VH1 related dual specific protein phosphatase Y antibody; Vaccinia virus VH1-related dual-specific protein phosphatase Y antibody; VH1 related member Y antibody; VH1-related member Y antibody; VHY antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human DUSP15
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6.; May play a role in the regulation of oligodendrocyte differentiation. May play a role in the regulation of myelin formation. Involved in the regulation of Erk1/2 phosphorylation in Schwann cells; the signaling may be linked to the regulation of myelination.
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基因功能參考文獻：
- The results showed that dual specificity phosphatase 15 (DUSP15) rs3746599 was significantly associated with autism under allelic, additive and dominant models,The findings initially suggest that DUSP15 might be a susceptibility gene for autism in Chinese Han population. PMID: 27223645
- Dusp15/VHY is a key regulator of oligodendrocyte differentiation, and PDGFR-beta and SNX6 are novel and specific Dusp15 substrates. PMID: 22792334
- VHY is a new member of a subgroup of myristoylated VH1-like small dual specificity phosphatases PMID: 15138252
- crystal structure of catalytic domain PMID: 16170801
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亞細胞定位：Cytoplasm.; [Isoform 3]: Cell membrane; Lipid-anchor; Cytoplasmic side.
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蛋白家族：Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
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組織特異性：Highly expressed in testis. Expressed in brain; up-regulated in patients with multiple sclerosis gray matter lesions.
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數據庫鏈接：
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