DET1 Antibody

中文名稱：

DET1兔多克隆抗體
貨號：

CSB-PA762572LA01HU
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA762572LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA762572LA01HU at dilution of 1:100
其他：

產(chǎn)品詳情

標(biāo)記方式：

Non-conjugated

本頁面中的產(chǎn)品，DET1 Antibody (CSB-PA762572LA01HU)，的標(biāo)記方式是Non-conjugated。對于DET1 Antibody，我們還提供其他標(biāo)記。見下表：

標(biāo)記方式	貨號	產(chǎn)品名稱	應(yīng)用
HRP	CSB-PA762572LB01HU	DET1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA762572LC01HU	DET1 Antibody, FITC conjugated
Biotin	CSB-PA762572LD01HU	DET1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is involved in JUN ubiquitination and degradation.
基因功能參考文獻(xiàn)：
1. promotes ubiquitination and degradation of c-Jun by assembling a multisubunit ubiquitin ligase containing DNA Damage Binding Protein-1 (DDB1), cullin 4A (CUL4A), Regulator of Cullins-1 (ROC1), and constitutively photomorphogenic-1 PMID: 14739464
2. These findings demonstrate that the conserved DET1 complex modulates Cul4A functions by a novel mechanism. PMID: 17452440
亞細(xì)胞定位：

Nucleus.
蛋白家族：

DET1 family
組織特異性：

Highly expressed in the ovary, some lymphoid organs and resting leukocytes.
數(shù)據(jù)庫鏈接：

HGNC: 25477

OMIM: 608727

KEGG: hsa:55070

STRING: 9606.ENSP00000408994

UniGene: Hs.655064

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