DEPP1 Antibody

中文名稱：

DEPP1兔多克隆抗體
貨號：

CSB-PA865135LA01HU
規格：

￥440
圖片：
IHC image of CSB-PA865135LA01HU diluted at 1:400 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Immunofluorescence staining of HepG2 cells with CSB-PA865135LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) DEPP1 Polyclonal antibody
Uniprot No.：

Q9NTK1
基因名：

DEPP1
別名：

Decidual protein induced by progesterone antibody; Depp antibody; DEPP_HUMAN antibody; Fasting-induced gene protein antibody; FIG antibody; Protein DEPP antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Protein DEPP1 protein (57-174AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，DEPP1 Antibody (CSB-PA865135LA01HU)，的標記方式是Non-conjugated。對于DEPP1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA865135LB01HU	DEPP1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA865135LC01HU	DEPP1 Antibody, FITC conjugated
Biotin	CSB-PA865135LD01HU	DEPP1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:200-1:500
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as a critical modulator of FOXO3-induced autophagy via increased cellular ROS.
基因功能參考文獻：
1. Knockdown of DEPP prevented the primary and secondary reactive oxygen species wave during FOXO3 activation. PMID: 25261981
2. C10orf10 expression is frequently decreased in breast cancer tissues and is associated with shorter survival times. PMID: 24936657
3. DEPP is regulated at the level of transcription by FoxO in human vascular endothelial cells PMID: 21510935
4. DEPP is a novel insulin-regulatory molecule expressed abundantly in insulin-sensitive tissues including white adipose tissue and liver. PMID: 19937567
5. Expressed in endothelial cells of peripheral tissues, but not in atrial or ventricular endocardial cells of the heart, unexpected degree of molecular heterogeneity among arterial endothelial cells, up-regulated in subsets of endothelial cells. PMID: 15977181
6. Depp modulates the effects of progesterone during decidualization and in the decidua by affecting gene expression. PMID: 16123073
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亞細胞定位：

Cytoplasm. Peroxisome. Mitochondrion.
組織特異性：

Expressed in various tissues, including pancreas, placenta, ovary, testis and kidney.
數據庫鏈接：

HGNC: 23355

OMIM: 611309

KEGG: hsa:11067

STRING: 9606.ENSP00000298295

UniGene: Hs.93675

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