DCUN1D5 Antibody
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中文名稱：DCUN1D5兔多克隆抗體
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貨號：CSB-PA006575GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：DCUN1D5
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別名：DCUN1D5DCN1-like protein 5 antibody; DCUN1 domain-containing protein 5 antibody; Defective in cullin neddylation protein 1-like protein 5 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human DCUN1D5
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IF
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which is necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs). May play a role in DNA damage response and may participate in cell proliferation and anchorage-independent cell growth.
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基因功能參考文獻：
- evidence that DCNL5 may be involved in innate immunity, as it is a direct substrate of the kinase IKKalpha during immune signalling. PMID: 29958295
- SCCRO5 has oncogenic potential that requires its function as a component of the neddylation E3. Neddylation activity and nuclear localization of SCCRO5 are important for its in vivo function. PMID: 24192928
- Overexpression of DCUN1D5 is associated with laryngeal squamous cell carcinoma. PMID: 23098533
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亞細胞定位：Nucleus. Cytoplasm, cytoskeleton, spindle.
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組織特異性：Weakly expressed in testis, skin and immune tissues (thymus, spleen and lymph nodes).
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數據庫鏈接：
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