CYP26C1 Antibody

中文名稱：

CYP26C1兔多克隆抗體
貨號：

CSB-PA751026LA01HU
規格：

￥440
圖片：
Immunofluorescence staining of HepG2 cells with CSB-PA751026LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) CYP26C1 Polyclonal antibody
Uniprot No.：

Q6V0L0
基因名：

CYP26C1
別名：

CP26C_HUMAN antibody; cyp26b1l antibody; CYP26C1 antibody; cyp26d1 antibody; Cytochrome P450 26C1 antibody; Cytochrome P450 family 26 subfamily C polypeptide 1 antibody; Cytochrome P450; subfamily XXVIC polypeptide 1 antibody; EG546726 antibody; FFDD4 antibody; FLJ45301 antibody; MGC158120 antibody; retinoic acid catabolizing enzyme antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Cytochrome P450 26C1 protein (331-460AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，CYP26C1 Antibody (CSB-PA751026LA01HU)，的標記方式是Non-conjugated。對于CYP26C1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA751026LB01HU	CYP26C1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA751026LC01HU	CYP26C1 Antibody, FITC conjugated
Biotin	CSB-PA751026LD01HU	CYP26C1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IF

推薦稀釋比：

Application	Recommended Dilution
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays a role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA (preferred substrate).
基因功能參考文獻：
1. Together, these findings describe CYP26C1 as the first genetic modifier for SHOX deficiency. PMID: 27861128
2. Elevated expression of CYP26C1 in primary breast carcinomas PMID: 26009309
3. Focal facial dermal dysplasia, type IV results from the loss of function mutations in CYP26C1. PMID: 23161670
4. CYP26A1 and CYP26C1 play a pivotal role in the pathogenesis of nonsyndromic bilateral and unilateral optic nerve aplasia. PMID: 21850183
5. may play a specific role in catabolizing both all-trans and 9-cis isomers of retinoic acid. PMID: 14532297
6. Observational study of gene-disease association. (HuGE Navigator) PMID: 16385451
7. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 19703508
8. Observational study of gene-disease association. (HuGE Navigator) PMID: 16933217
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相關疾病：

Focal facial dermal dysplasia 4 (FFDD4)
亞細胞定位：

Membrane; Single-pass membrane protein.
蛋白家族：

Cytochrome P450 family
組織特異性：

Detected in most tissues at very low level.
數據庫鏈接：

HGNC: 20577

OMIM: 608428

KEGG: hsa:340665

STRING: 9606.ENSP00000285949

UniGene: Hs.369993

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