CTDSP2 Antibody
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中文名稱：CTDSP2兔多克隆抗體
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貨號：CSB-PA006143GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：CTDSP2
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別名：Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 2 antibody; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 antibody; conserved gene amplified in osteosarcoma 4 antibody; conserved gene amplified in osteosarcoma antibody; CTDS2_HUMAN antibody; Ctdsp2 antibody; NIF2 antibody; NLI interacting factor 2 antibody; NLI-interacting factor 2 antibody; Nuclear LIM interactor interacting factor 2 antibody; Nuclear LIM interactor-interacting factor 2 antibody; OS4 antibody; Protein OS 4 antibody; Protein OS-4 antibody; PSR2 antibody; SCP2 antibody; Small C-terminal domain phosphatase 2 antibody; Small CTD phosphatase 2 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human CTDSP2
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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功能：Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.
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基因功能參考文獻：
- CTDSP2 induces p21(Cip1/Waf1) through increasing the activity of Ras. PMID: 25990325
- These results suggest that SCP2 is involved in promoter clearance during steroid-activated transcription. PMID: 16724108
- SCP2 acts as a phosphatase for regulatory phosphorylations in the linker region of Smad1 and Smad2 PMID: 17085434
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亞細胞定位：Nucleus.
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組織特異性：Expression is restricted to non-neuronal tissues. Highest expression in pancreas and lowest in liver.
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數(shù)據(jù)庫鏈接：
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