CTDNEP1 Antibody

中文名稱：

CTDNEP1兔多克隆抗體
貨號：

CSB-PA05415A0Rb
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA05415A0Rb at dilution of 1:100

Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA05415A0Rb at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) CTDNEP1 Polyclonal antibody
Uniprot No.：

O95476
基因名：

CTDNEP1
別名：

CTDNEP1; DULLARD; CTD nuclear envelope phosphatase 1; Serine/threonine-protein phosphatase dullard
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human CTD nuclear envelope phosphatase 1 protein (3-244AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，CTDNEP1 Antibody (CSB-PA05415A0Rb)，的標記方式是Non-conjugated。對于CTDNEP1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA05415B0Rb	CTDNEP1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA05415C0Rb	CTDNEP1 Antibody, FITC conjugated
Biotin	CSB-PA05415D0Rb	CTDNEP1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol. May antagonize BMP signaling.
基因功能參考文獻：
1. CTDNEP1 is upregulated in non-alcoholic fatty liver disease. Up-regulation of miR-122 can trigger the compensatory response of LPIN1 and CTDNEP1 in hepatosteatosis. PMID: 28287811
2. Dullard participates in a unique phosphatase cascade regulating nuclear membrane biogenesis, a cascade that is conserved from yeast to mammals. PMID: 17420445
亞細胞定位：

Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein.
蛋白家族：

Dullard family
組織特異性：

Muscle specific with lower expression in other metabolic tissues.
數據庫鏈接：

HGNC: 19085

OMIM: 610684

KEGG: hsa:23399

STRING: 9606.ENSP00000321732

UniGene: Hs.513913

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