CST7 Antibody
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中文名稱：CST7兔多克隆抗體
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貨號：CSB-PA006095ESR2HU
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規格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA006095ESR2HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA006095ESR2HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) CST7 Polyclonal antibody
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Uniprot No.：
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基因名：CST7
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別名：CMAP antibody; CST 7 antibody; Cst7 antibody; Cystatin 7 antibody; cystatin F (leukocystatin) antibody; Cystatin like metastasis associated protein antibody; Cystatin-7 antibody; Cystatin-F antibody; Cystatin-like metastasis-associated protein antibody; Cystatin7 antibody; CystatinF antibody; CYTF_HUMAN antibody; dJ568C11.1 antibody; Leukocystatin antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Cystatin-F protein (20-145AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system.
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基因功能參考文獻：
- during monocyte to macrophage differentiation, the endosomal/lysosomal proteolytic activity can be regulated by cystatin F whose expression is under the control of transcriptional factor C/EBP alpha. PMID: 30033148
- Regulation of cathepsins S and L by cystatin F during maturation of dendritic cells. PMID: 22365146
- Transgenic cystatin F is expressed in model mice only during demyelination; in chronic demyelination, remyelinating ability is lost. PMID: 21344476
- cystatin F is an intracellular cysteine peptidase inhibitor with readily regulated expression PMID: 12423348
- CST7 is secreted, but artificial modification of its C-terminus can induce its endocytic targeting. PMID: 15212960
- Cystatin F was not colocalized with cystatin C shich suggests distinct functions for these two cysteine protease inhibitors in U937 cells. PMID: 15752368
- analysis of reduction-dependent activation of human cystatin F PMID: 16601115
- A latent protease inhibitor which is itself regulated by proteolysis in the endocytic pathway. PMID: 18256700
- Data demonstrate the addition of N-linked sugars to an Asn-X-Cys motif in cystatin F and suggest that the mannose 6-phosphate sorting machinery is used to divert cystatin F from the secretory pathway and to mediate its uptake from extracellular pools. PMID: 19192250
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亞細胞定位：Secreted. Cytoplasm.
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蛋白家族：Cystatin family
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組織特異性：Primarily expressed in peripheral blood cells and spleen.
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數據庫鏈接：
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