COX15 Antibody
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中文名稱：COX15兔多克隆抗體
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貨號：CSB-PA759167LA01HU
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規格：￥440
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圖片：
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Western Blot
Positive WB detected in: Rat kidney tissue
All lanes: COX15 antibody at 3.4μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 47, 44 kDa
Observed band size: 47 kDa -
IHC image of CSB-PA759167LA01HU diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) COX15 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：CEMCOX2 antibody; COX15 antibody; COX15 homolog; cytochrome c oxidase assembly protein antibody; COX15; S. cerevisiae; homolog of antibody; COX15_HUMAN antibody; cytochrome c oxidase assembly homolog 15 (yeast) antibody; Cytochrome c oxidase assembly protein COX15 homolog antibody; cytochrome c oxidase subunit 15 antibody
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宿主：Rabbit
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反應種屬：Human, Rat
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免疫原：Recombinant Human Cytochrome c oxidase assembly protein COX15 homolog protein (1-67AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，COX15 Antibody (CSB-PA759167LA01HU)，的標記方式是Non-conjugated。對于COX15 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:5000 IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：May be involved in the biosynthesis of heme A.
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基因功能參考文獻：
- Mutations of COX15 causing single amino acid conversions are associated with fatal infantile hypertrophic cardiomyopathy and the neurological disorder Leigh syndrome. PMID: 26940873
- Mutations in COX15 produce a defect in the mitochondrial heme biosynthetic pathway, causing early-onset fatal hypertrophic cardiomyopathy PMID: 12474143
- A patient with typical clinical and neuroradiological features of Leigh syndrome and cytochrome oxidase deficiency was found to have a mutation in the COX15 gene. PMID: 15235026
- cdkl3 transfected in anchorage-independent (suspension) HeLa cells overexpressed relative to attached cells and lead to elevated proliferation and viability relative to untransfected. Same in two HEK-293 and a CHO cell lines. PMID: 17945021
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相關疾病：Cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 2 (CEMCOX2); Leigh syndrome (LS)
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亞細胞定位：Mitochondrion membrane; Multi-pass membrane protein.
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蛋白家族：COX15/CtaA family
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組織特異性：Predominantly found in tissues characterized by high rates of oxidative phosphorylation (OxPhos), including muscle, heart, and brain.
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數據庫鏈接：
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