COX10 Antibody
-
中文名稱：COX10兔多克隆抗體
-
貨號：CSB-PA621520ESR1HU
-
規格：￥440
-
圖片：
-
Western blot
All lanes: COX10 antibody at 5.31μg/ml + Mouse gonadal tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 49, 28 kDa
Observed band size: 49 kDa -
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA621520ESR1HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA621520ESR1HU at dilution of 1:100
-
-
其他：
產品詳情
-
產品名稱：Rabbit anti-Homo sapiens (Human) COX10 Polyclonal antibody
-
Uniprot No.：
-
基因名：
-
別名：2410004F01Rik antibody; AU042636 antibody; COX10 antibody; COX10_HUMAN antibody; Cytochrome c oxidase assembly protein antibody; Cytochrome c oxidase subunit X antibody; Heme A farnesyltransferase antibody; Heme O synthase antibody; OTTMUSP00000006085 antibody; Protoheme IX farnesyltransferase; mitochondrial antibody; Protoheme IX farnesyltransferase; mitochondrial precursor antibody; RP23-78H18.1 antibody
-
宿主：Rabbit
-
反應種屬：Human, Mouse
-
免疫原：Recombinant Human Protoheme IX farnesyltransferase, mitochondrial protein (1-160AA)
-
免疫原種屬：Homo sapiens (Human)
-
標記方式：Non-conjugated
-
克隆類型：Polyclonal
-
抗體亞型：IgG
-
純化方式：Antigen Affinity Purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
-
產品提供形式：Liquid
-
應用范圍：ELISA, WB, IHC
-
推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 -
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
功能：Converts protoheme IX and farnesyl diphosphate to heme O.
-
基因功能參考文獻：
- On the basis of its pivotal role in regulating cell death upon COX dysfunction, CerS6 might potentially represent a novel target for therapeutic intervention in mitochondrial diseases caused by COX dysfunction. PMID: 25766330
- ISCU and COX10 are target genes of miR-210 related to mitochondrial metabolism PMID: 20498629
- COX 15 mRNA was significantly more abundant in the cerebral tissue of Alzheimer's disease (AD) patients and COX10 and COX15 SNP were significantly less represented in the patient group, suggesting a possible protective role toward the risk for AD PMID: 19826901
- The expression of the AOX, well-tolerated by the cells, compensates for both the growth defect and the pronounced oxidant-sensitivity of COX-deficient human cells. PMID: 20049701
- Cytochrome c oxidase is decreased significantly in platelets and hippocampus in Alzheimer patients compared to controls. PMID: 11959398
- COX10 has a role in mitochondrial heme A biosynthesis PMID: 12928484
- This study report a cytochrome c oxidase (COX)-deficient patient, clinically affected with Leigh-like disease, with a homozygous mutation in the COX10 start codon. PMID: 15455402
- Geranylgeranyltransferase inhibitor-2147 (GGTI-2147), an inhibitor of this enzyme prenylation, elicited significant inhibition of glucose-stimulated insulin secretion from INS 832/13 islet cells. PMID: 17192483
顯示更多
收起更多
-
相關疾病：Mitochondrial complex IV deficiency (MT-C4D); Leigh syndrome (LS)
-
亞細胞定位：Mitochondrion membrane; Multi-pass membrane protein.
-
蛋白家族：UbiA prenyltransferase family
-
數據庫鏈接：
Most popular with customers
-
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
-
