COPS4 Antibody
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中文名稱：COPS4兔多克隆抗體
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貨號：CSB-PA880098ESR2HU
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規(guī)格：￥440
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圖片：
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Western blot
All lanes: COPS4 antibody at 8μg/ml
Lane 1: Hela whole cell lysate
Lane 2: HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 47, 41 kDa
Observed band size: 47 kDa -
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA880098ESR2HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA880098ESR2HU at dilution of 1:100
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) COPS4 Polyclonal antibody
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Uniprot No.：
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基因名：COPS4
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別名：CH4 antibody; COP9 (constitutive photomorphogenic) homolog subunit 4 antibody; COP9 complex homolog subunit 4 antibody; COP9 complex S4 antibody; COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) antibody; COP9 constitutive photomorphogenic homolog subunit 4 antibody; COP9 signalosome complex subunit 4 antibody; COP9 signalosome subunit 4 antibody; COPS4 antibody; CSN complex subunit 4 antibody; CSN4 antibody; CSN4 SCHPO antibody; CSN4_HUMAN antibody; DCH4 antibody; JAB1 containing signalosome subunit 4 antibody; JAB1-containing signalosome subunit 4 antibody; MGC94896 antibody; SGN4 antibody; Signalosome subunit 4 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human COP9 signalosome complex subunit 4 protein (1-310AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:200-1:1000 IHC 1:20-1:200 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. Also involved in the deneddylation of non-cullin subunits such as STON2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1, IRF8/ICSBP and SNAPIN, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
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基因功能參考文獻(xiàn)：
- Identified is a novel-binding partner of torsin A, the subunit 4 (CSN4) of CSN signalosome. PMID: 21102408
- Level in fetal Down syndrome brain found to be comparable to that of controls. PMID: 11824616
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亞細(xì)胞定位：Cytoplasm. Nucleus. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle.
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蛋白家族：CSN4 family
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數(shù)據(jù)庫鏈接：
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