COL14A1 Antibody
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中文名稱：COL14A1兔多克隆抗體
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貨號：CSB-PA196447
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規格：￥2024
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圖片：
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Immunohistochemistry analysis of paraffin-embedded human heart tissue using Collagen XIV α1 antibody. -
Immunofluorescence analysis of HeLa cells, using Collagen XIV α1 antibody.
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) COL14A1 Polyclonal antibody
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Uniprot No.：
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基因名：COL14A1
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Synthesized peptide derived from internal of Human Collagen XIV α1.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Polyclonal
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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產品提供形式：Liquid
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應用范圍：ELISA,IHC,IF
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推薦稀釋比：
Application Recommended Dilution IHC 1:50-1:100 IF 1:100-1:500 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Plays an adhesive role by integrating collagen bundles. It is probably associated with the surface of interstitial collagen fibrils via COL1. The COL2 domain may then serve as a rigid arm which sticks out from the fibril and protrudes the large N-terminal globular domain into the extracellular space, where it might interact with other matrix molecules or cell surface receptors.
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基因功能參考文獻：
- the intima+media of IPAH vessels, collagens (COL4A5, COL14A1, and COL18A1), matrix metalloproteinase (MMP) 19, and a disintegrin and metalloprotease (ADAM) 33 were higher expressed, whereas MMP10, ADAM17, TIMP1, and TIMP3 were less abundant. PMID: 25840998
- COL14A1 would be a casual gene for punctate palmoplantar keratoderma. PMID: 22972947
- In addition to binding collagen I, COMP binds to collagens XII and XIV via their C-terminal collagenous domains. PMID: 22573329
- Results suggest that collagens XII and XIV might serve different functions during human embryonic development although their structures are highly similar. PMID: 15609093
- the fibronectin type III domain of collagen XIV is an inducer of quiescence and differentiation in fibroblasts and preadipocytes PMID: 16129687
- The aim of this study was therefore to test the association between polymorphisms within COL12A1 and COL14A1 and Achilles tendon injuries PMID: 17960519
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亞細胞定位：Secreted, extracellular space, extracellular matrix.
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蛋白家族：Fibril-associated collagens with interrupted helices (FACIT) family
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數據庫鏈接：
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