CNTROB Antibody
-
中文名稱：CNTROB兔多克隆抗體
-
貨號：CSB-PA001554
-
規格：￥1090
-
圖片：
-
Western Blot analysis of HuvEc cells using Centrobin Polyclonal Antibody
-
-
其他：
產品詳情
-
Uniprot No.：
-
基因名：CNTROB
-
別名：9830165K03Rik antibody; Centrobin antibody; centrobin; centrosomal BRCA2 interacting protein antibody; Centrosomal BRCA2 interacting protein antibody; Centrosomal BRCA2-interacting protein antibody; CNTRB_HUMAN antibody; Cntrob antibody; LIP8 antibody; LYST interacting protein 8 antibody; LYST-interacting protein 8 antibody; LYST-interacting protein LIP8 antibody; PP1221 antibody; RGD1307488 antibody; RP23 26L6.9 antibody
-
宿主：Rabbit
-
反應種屬：Human
-
免疫原：Synthesized peptide derived from the Internal region of Human Centrobin.
-
免疫原種屬：Homo sapiens (Human)
-
標記方式：Non-conjugated
-
抗體亞型：IgG
-
純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
-
產品提供形式：Liquid
-
應用范圍：WB, IHC, ELISA
-
推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:5000 -
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
功能：Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis.
-
基因功能參考文獻：
- cytoplasmic centrobin has roles in noncentrosomal microtubule formation in specific cell types and during the cell cycle PMID: 26083938
- it is proposed that Centrobin might regulate microtubule nucleation and organization by controlling the amount of pericentriolar matrix PMID: 23442802
- NEK2 phosphorylation antagonizes the microtubule stabilizing activity of centrobin. PMID: 23291182
- Our results indicate that genetic polymorphisms of centrobin and Nek2 are related to breast cancer susceptibility in Chinese Han women. PMID: 23001753
- Centrobin facilitates the elongation and stability of centrioles via its interaction with tubulins. PMID: 21576394
- Data propose that centrobin functions as a microtubule stabilizing factor and PLK1 enhances centrobin activity for proper spindle formation during mitosis. PMID: 20511645
- a requirement of Centrobin in maintaining centrosome integrity, which in turn promotes anchoring of mitotic spindle to the centrosomes. PMID: 20190801
- Inhibition of p38 activity or downregulation of p38 expression could overcome the cell-cycle arrest caused by centrobin depletion. PMID: 20085806
- Centrobin is a centriole-associated protein that asymmetrically localizes to the daughter centriole. PMID: 16275750
- Results report that NIP2, previously identified as centrobin, is a novel substrate of Nek2, and that NIP2 has a role in stabilizing the microtubule structure. PMID: 17535851
顯示更多
收起更多
-
亞細胞定位：Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Centriole-associated, asymmetrically localizes to the daughter centriole.
-
組織特異性：Widely expressed (at protein level). Highly expressed in testis. Also expressed in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes.
-
數據庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
