Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA005657LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA005657LA01HU at dilution of 1:100
Immunofluorescent analysis of Hela cells using CSB-PA005657LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Western Blot
Positive WB detected in: Mouse liver tissue
All lanes: CNN3 antibody at 3.4μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 37, 32 kDa
Observed band size: 37 kDa
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
基因功能參考文獻:
These results reveal the importance of the MEKK1-calponin-3 signaling pathway to cell contractility. PMID: 27528401
overexpressed CNN3 during sonic vibration increases expression of glutamate receptors and promotes functional neural differentiation of human umbilical cords-mesenchymal stem cells. PMID: 26175098
CNN3 as a new pro-invasive protein in trophoblast cells that is induced under low oxygen conditions. PMID: 25050546
Participates in actin stress fiber remodeling PMID: 23545751
The mRNA and protein level of calponin-3 were increase expression in brain in patiens with epilepsy. PMID: 22119193
Results indicate that CNN3 regulates actin cytoskeleton rearrangement which is required for the plasma membranes of trophoblasts to become fusion competent. PMID: 20861310
These results suggest a role of calponin 3 in the regulation of Bone morphogenetic proteins -dependent cellular responses. PMID: 17825283
Gene rearrangements of CNN3 is associated with mucosa-associated lymphoid tissue lymphoma. PMID: 18927281
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蛋白家族:
Calponin family
組織特異性:
Expressed in both non-smooth muscle tissues as well as smooth muscle tissues.