CLIC3 Antibody
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中文名稱：CLIC3兔多克隆抗體
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貨號：CSB-PA070203
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規格：￥1090
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其他：
產品詳情
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Uniprot No.：
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基因名：CLIC3
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別名：CLIC3; Chloride intracellular channel protein 3
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宿主：Rabbit
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反應種屬：Human
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免疫原：Synthesized peptide derived from the Internal region of Human CLIC3.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：WB, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 ELISA 1:40000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Can insert into membranes and form chloride ion channels. May participate in cellular growth control.
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基因功能參考文獻：
- CLIC3 is also secreted by cancer cells, is abundant in the stromal and tumour compartments of aggressive ovarian cancers and its levels correlate with poor clinical outcome. PMID: 28198360
- in malignant pleural mesothelioma, the gene expressions of CLIC3 and CLIC4 were significantly increased compared to controls PMID: 26445368
- CLIC3 controls trafficking of late endosomal MT1-MMP and dictates invasion and metastasis in breast cancer. PMID: 25015290
- results suggest that increased expression of chloride intracellular channel 3 (CLIC3) may play a role in abnormal placental function associated with the human pregnancy disorders fetal growth restrict and pre-eclampsia PMID: 22795578
- The structure of the soluble form of CLIC3, is presented. PMID: 20146363
- CLIC3 facilitates chloride ion movement and regulates cellular processes associated with the movement of chloride in placental and fetal membrane cells. PMID: 17027078
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亞細胞定位：Nucleus. Membrane; Single-pass membrane protein. Cytoplasm.
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蛋白家族：Chloride channel CLIC family
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組織特異性：Detected in placenta (at protein level). Widely expressed. High expression is found in placenta followed by lung and heart. Low expression in skeletal muscle, kidney and pancreas.
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數據庫鏈接：
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