CLGN Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

O14967
基因名：

CLGN
別名：

CLGN; Calmegin
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human CLGN
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Functions during spermatogenesis as a chaperone for a range of client proteins that are important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. Required for normal sperm migration from the uterus into the oviduct. Required for normal male fertility. Binds calcium ions.
基因功能參考文獻(xiàn)：
1. In gene-based analysis CLGN1 represented one of a cluster of genes, which interacted with sodium to influence Blood Pressure. PMID: 27271309
2. Although their similarity in carbohydrate binding specificities is high, there seems to be some differences in the mode of substrate recognition between calmegin and calnexin. PMID: 24769397
3. calmegin expression is regulated by histone deacetylase and CpG methyltransferase in a coordinative way PMID: 16264275
亞細(xì)胞定位：

Endoplasmic reticulum membrane; Single-pass type I membrane protein.
蛋白家族：

Calreticulin family
組織特異性：

Detected in testis (at protein level). Detected in testis.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 2060

OMIM: 601858

KEGG: hsa:1047

STRING: 9606.ENSP00000326699

UniGene: Hs.86368

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