Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Activates apoptosis.; (Microbial infection) Involved in Hepatatis C virus (HCV) assembly and required for HCV entry into hepatocytes.
基因功能參考文獻:
High Cideb expression is associated with Ulcerative Colitis. PMID: 28719542
CIDEB interacts with the HCV NS5A protein, and the N terminus of CIDEB and the domain I of NS5A are involved in this interaction. PMID: 27282740
these data revealed that Cideb plays an important role in controlling intestinal chylomicron lipidation. PMID: 24831470
this study shows that C5a signaling induces apoptosis in brain vascular endothelial cells in experimental lupus through activation of CIDEB PMID: 27213693
CIDEB downregulation may contribute to HCV-induced hepatic steatosis PMID: 26865724
CIDEB can act as an anti-HCV host factor and contribute to altered triglyceride homeostasis. PMID: 24980280
Authors found CIDEB to be an essential cofactor for hepatitis C virus entry into hepatocytes. PMID: 24829338
this work highlights CIDEB's role in lipid droplet (LD) fusion, and presents a new model system to study the PGC-1alpha/CIDEB pathway's role in LD dynamics and the VLDL pathway. PMID: 24161736
CIDE proteins expression correlate with tumor and survival characteristics in patients with renal cell carcinoma. PMID: 23475172
A novel mechanism for the cell-specific transcription of the human CIDE-B gene, which involves epigenetic and genetic control at separate respective promoters is reported. PMID: 16248853
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組織特異性:
Highly expressed in liver and small intestine and, at lower levels, in colon, kidney and spleen.