CHRD Antibody
-
中文名稱：CHRD兔多克隆抗體
-
貨號：CSB-PA875601
-
規(guī)格：￥1090
-
圖片：
-
Immunohistochemical analysis of paraffin-embedded human-liver-cancer, antibody was diluted at 1:200 -
Immunohistochemical analysis of paraffin-embedded human-liver-cancer, antibody was diluted at 1:200
-
-
其他：
產品詳情
-
Uniprot No.：
-
基因名：
-
別名：CHRD antibody; UNQ217/PRO243Chordin antibody
-
宿主：Rabbit
-
反應種屬：Human,Mouse,Rat
-
免疫原：Synthetic peptide from Human protein at AA range: 905-954
-
免疫原種屬：Homo sapiens (Human)
-
標記方式：Non-conjugated
-
純化方式：The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
-
產品提供形式：Liquid
-
應用范圍：IHC,ELISA
-
推薦稀釋比：
Application Recommended Dilution IHC IHC-p:1:50-300 ELISA 1:10000-20000 -
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
功能：Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.
-
基因功能參考文獻：
- Data suggest CHRD (chordin) cleavage by tolloid-like metalloproteinases is insufficient to regulate BMP(bone morphogenetic protein)/BMPR signaling; CHRD fragments and TSG (twisted gastrulation protein) contribute to inhibition of BMP/BMPR signaling. PMID: 26517884
- C-terminal chordin domains play an important role in Bone morphogenetic protein regulation. PMID: 25157165
- chordin silencing increased osteogenic differentiation without supplemented BMP-2. PMID: 23931154
- results suggest that CHRD could participate in regulating BMP activity in normal ovarian surface epithelium physiology, and that its mis-expression in ovarian surface epithelium may facilitate cancer incidence and/or progression PMID: 16449796
- Bone morphogenetic protein (BMP) chordin is produced endogenously during osteogenic differentiation of human mesenchymal stem cells (MSCs); blockade of bone morphogenetic inhibitor chordin increases the rate of osteogenic differentiation of MSCs in vitro. PMID: 18533030
- Noggin and chordin were also expressed most intensely in areas of cartilage formation and there was no difference in their expression between the non-hypertrophic and hypertrophic chondrocytes. PMID: 19023570
- there was no difference in the expression of the noggin and chordin between healing and nonhealing fractures PMID: 19058174
- Alternatively spliced variants have different patterns of expression to influence BMP activity in varying physiolgical situations. PMID: 11472837
顯示更多
收起更多
-
亞細胞定位：Secreted.
-
蛋白家族：Chordin family
-
組織特異性：Expressed at the highest level in liver.
-
數(shù)據(jù)庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
