CGNL1 Antibody
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中文名稱：CGNL1兔多克隆抗體
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貨號(hào)：CSB-PA005304GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：CGNL1
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別名：Cgnl1 antibody; CGNL1_HUMAN antibody; Cingulin like 1 antibody; Cingulin-like protein 1 antibody; FLJ14957 antibody; JACOP antibody; Junction-associated coiled-coil protein antibody; KIAA1749 antibody; MGC138254 antibody; Paracingulin antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human CGNL1
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
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靶點(diǎn)詳情
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功能：May be involved in anchoring the apical junctional complex, especially tight junctions, to actin-based cytoskeletons.
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基因功能參考文獻(xiàn)：
- demonstrate in a postnatal retinal vascular development model in mice that Cgnl1 function is crucial for sustaining neovascular growth and stability PMID: 29016873
- Results indentify plausible candidates include non-recurrent deletions at the glutamate transporter gene SLC1A1, a CNV locus recently suggested to be involved in schizophrenia through linkage analysis, and duplications at 1p36.33 and CGNL1. PMID: 24163246
- ZO-1 and PLEKHA7 are paracingulin-interacting proteins that are involved in its recruitment to epithelial tight and adherens junctions, respectively PMID: 21454477
- Paracingulin regulates the activity of Rac1 and RhoA GTPases by recruiting Tiam1 and GEF-H1 to epithelial junctions PMID: 18653465
- This paper studied the mouse JACOP protein and found that the JACOP protein has structural and functional similarities to cingulin. PMID: 15292197
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相關(guān)疾?。?/div>Aromatase excess syndrome (AEXS)亞細(xì)胞定位：Cell junction, tight junction.蛋白家族：Cingulin family組織特異性：Smooth muscle, spleen, testis, fetal brain, amygdala, corpus callosum, cerebellum, thalamus and subthalamic nucleus of adult brain.數(shù)據(jù)庫(kù)鏈接：
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