CCT6A Antibody
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中文名稱：CCT6A兔多克隆抗體
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貨號：CSB-PA796607
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規格：￥2024
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圖片：
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using CCT6A antibody. -
Western blot analysis of extracts from HepG2 cells, using CCT6A antibody. -
Western blot analysis of extracts from cos-7 cells (Lane 2) and 293 cells (Lane 3), using CCT6A antiobdy. The lane on the left is treated with synthesized peptide.
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) CCT6A Polyclonal antibody
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Uniprot No.：
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基因名：CCT6A
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宿主：Rabbit
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反應種屬：Human
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免疫原：Synthesized peptide derived from internal of Human CCT6A.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Polyclonal
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:3000 IHC 1:50-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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功能：Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. The TRiC complex plays a role in the folding of actin and tubulin (Probable).
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基因功能參考文獻：
- High expression of CCT6A is associated with Non-Small Cell Lung Cancer. PMID: 28104536
- selective inhibition of SMAD3 or CCT6A efficiently suppresses TGF-beta-mediated metastasis. Findings provide a mechanism that directs TGF-beta signaling toward its prometastatic arm and may contribute to the development of therapeutic strategies targeting TGF-beta for non-small-cell lung carcinoma. PMID: 28375158
- These data suggest that CCT6A is a novel autoantigen recognized by Vdelta2 gammadelta T cells, which deepens our understanding of mechanisms in autoimmune diseases. PMID: 27489109
- identified genes, which include Tcp20, may play important role in conferring radioresistance to oral squamous cell carcinoma and could be useful in identifying cases with more radioresistance PMID: 16211299
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亞細胞定位：Cytoplasm.
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蛋白家族：TCP-1 chaperonin family
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數據庫鏈接：
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