CCT5 Antibody
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中文名稱：CCT5兔多克隆抗體
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貨號：CSB-PA111204
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規格：￥2024
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圖片：
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Western blot analysis of extracts from HepG2 cells, using CCT5 antibody.
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) CCT5 Polyclonal antibody
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Uniprot No.：
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基因名：CCT5
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宿主：Rabbit
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反應種屬：Human
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免疫原：Synthesized peptide derived from internal of Human CCT5.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Polyclonal
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:3000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.
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基因功能參考文獻：
- CCT5 complex caps mutant mHTT fibrils at their tips and encapsulates mHTT oligomers, providing a structural description of the inhibition of mHTTQ46-Ex1 by CCT5 complex and a shared mechanism of mHTT inhibition between TRiC chaperonin and the CCT5 complex PMID: 25995452
- H147R CCT5 was not as efficient in chaperoning these substrates as wild type CCT5. PMID: 25124038
- introduction of the truncated human CCT epsilon subunit into yeast cells PMID: 22232265
- A missense mutation within the CCT5 gene is associated with autosomal recessive mutilating sensory neuropathy with spastic paraplegia. PMID: 16399879
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相關疾病：Neuropathy, hereditary sensory, with spastic paraplegia, autosomal recessive (HSNSP)
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亞細胞定位：Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
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蛋白家族：TCP-1 chaperonin family
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數據庫鏈接：
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