CCT3 Antibody
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中文名稱：CCT3兔多克隆抗體
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貨號：CSB-PA004857ESR1HU
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規格：￥440
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圖片：
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Western blot
All lanes: T-complex protein 1 subunit gamma antibody at 12μg/ml + Mouse brain tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 61, 57 kDa
Observed band size: 61 kDa -
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA004857ESR1HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA004857ESR1HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) CCT3 Polyclonal antibody
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Uniprot No.：
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基因名：CCT3
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別名：CCT 3 antibody; CCT gamma antibody; CCT-gamma antibody; CCT3 antibody; CCTG antibody; Chaperonin containing TCP1 subunit 3 (gamma) antibody; Chaperonin containing TCP1 subunit 3 antibody; hTRiC5 antibody; PIG48 antibody; T complex protein 1 gamma subunit antibody; T complex protein 1 subunit gamma antibody; T-complex protein 1 subunit gamma antibody; TCP 1 gamma antibody; TCP-1-gamma antibody; TCP1 (t complex 1) ring complex polypeptide 5 antibody; TCPG_HUMAN antibody; TRIC5 antibody
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宿主：Rabbit
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反應種屬：Human, Mouse
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免疫原：Recombinant Human T-complex protein 1 subunit gamma protein (1-300AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.
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基因功能參考文獻：
- Suggest that CCT3 is indispensible for hepatocellular carcinoma cell proliferation, and provides a potential drug target for treatment of HCC. PMID: 26739059
- Overexpression of CCT3 in the nuclei of cancerous cells is associated with hepatocellular carcinoma progression. CCT3 may be a target that affects the activation of STAT3 in HCC. PMID: 26229401
- Expression of S100A9 and CCTgamma was significantly elevated in liver tissue of patients with cholangiocarcinoma compared with controls. PMID: 23868055
- Among ten hepatocellular carcinoma cases with amplicon 1q21-q22, significant gene expression level of JTB, SHC1, CCT3 and COPA in the tumors than the paired adjacent non-malignant liver tissues. PMID: 12586295
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亞細胞定位：Cytoplasm.
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蛋白家族：TCP-1 chaperonin family
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數據庫鏈接：
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