CCHCR1 Antibody
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中文名稱：CCHCR1兔多克隆抗體
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貨號：CSB-PA004769ESR1HU
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規格：￥440
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圖片：
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Western blot
All lanes: CCHCR1 antibody at 2.67 μg/ml + 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 89, 100, 96 kDa
Observed band size: 89 kDa -
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA004769ESR1HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) CCHCR1 Polyclonal antibody
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Uniprot No.：
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基因名：CCHCR1
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別名：CCHCR1 antibody; C6orf18 antibody; HCR antibody; Coiled-coil alpha-helical rod protein 1 antibody; Alpha-helical coiled-coil rod protein antibody; Putative gene 8 protein antibody; Pg8 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Coiled-coil alpha-helical rod protein 1 protein (483-782AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：May be a regulator of keratinocyte proliferation or differentiation.
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基因功能參考文獻：
- psoriasis candidate gene CCHCR1 expressed at P-bodies and centrosomes PMID: 29866042
- CCHCR1 interacts specifically with the E2 protein of human papillomavirus type 16 on a surface overlapping BRD4 binding PMID: 24664238
- Confocal imaging confirmed the localization of CCHCR1 in P-bodies. PMID: 24858563
- The centrosomal localization of CCHCR1 provides a connection to the abnormal cell proliferation and offers a link to possible cellular pathways altered in psoriasis. PMID: 23189171
- Psoriasis is associated with genetic polymorphism in the CCHCR1 gene and in a genomic segment flanking the HLA-C region in the North Indian population. PMID: 22182809
- Isolated by a two hybrid assay, StAR binding protein binds StAR protein in cells and enhances the ability of StAR protein to promote syntheses of steroid hormones.(sTAR binding protein) PMID: 12909641
- These studies show that miR-122, a 22-nucleotide microRNA, is derived from a liver-specific noncoding polyadenylated RNA transcribed from the gene hcr. PMID: 17179747
- These results suggest a role for CCHCR1 in the pathogenesis of psoriasis via the regulation of skin steroid metabolism. PMID: 17221218
- Results show that HLA-Cw6 and CCHCR1 risk allele associations with clinical features of psoriasis are predictably highly similar in a Finnish nationwide cohort of 379 psoriasis patients. PMID: 17340018
- the aberrant function of CCHCR1 may lead to abnormal keratinocyte proliferation which is a key feature of psoriatic epidermis. PMID: 18174193
- CCHCR1 is up-regulated in skin cancer and associated with EGFR expression PMID: 19551138
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亞細胞定位：Cytoplasm. Nucleus.
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組織特異性：Found in all tissues tested, abundantly expressed in heart, liver, skeletal muscle, kidney and pancreas, and to a lesser extent in lung and placenta. Overexpressed in keratinocytes of psoriatic lesions.
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數據庫鏈接：
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