CADM4 Antibody
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中文名稱：CADM4兔多克隆抗體
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貨號：CSB-PA207693
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規(guī)格：￥2024
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圖片：
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Western blot analysis of extracts from RAW264.7 cells, using CADM4 antibody. -
Immunohistochemistry analysis of paraffin-embedded human brain tissue using CADM4 antibody. -
Immunofluorescence analysis of A549 cells, using CADM4 antibody.
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) CADM4 Polyclonal antibody
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Uniprot No.：
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基因名：CADM4
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Synthesized peptide derived from internal of Human CADM4.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Polyclonal
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB,IHC,IF
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:3000 IHC 1:50-1:100 IF 1:100-1:500 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
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功能：Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity.
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基因功能參考文獻：
- There was a significant association between RNase 5 and histological differentiation in colon adenocarcinomas, but no association between RNase 5 and Necl 4 in gastric or colon adenocarcinomas PMID: 28561015
- Low CADM4 expression is associated with bone marrow metastasis in neuroblastoma. PMID: 28921546
- The results suggest that Necl-4 enhances VEGF-induced activation of PLCgamma-c-Raf-MEK-ERK pathway without affecting the phosphorylation and internalization of VEGFR2. PMID: 28601637
- Necl-4 serves as a novel regulator for contact inhibition of cell movement and proliferation cooperatively with the VEGF receptor and PTPN13 PMID: 25893857
- results indicate that Necl-4 serves as a tumor suppressor by inhibiting the ErbB2/ErbB3 signaling and hemidesmosome disassembly PMID: 23611113
- Loss or decrease of CADM4 expression seems to play an important role in breast cancer invasiveness, and it is associated with poorer biological parameters. PMID: 23559354
- Cadm4 regulates the growth of the myelin unit and the organization of the underlying axonal membrane. PMID: 23825401
- CADM4, as well as 4.1B is expressed specifically in human proximal tubules. PMID: 21544807
- Nec- 4 suppress the growth and tumorigenic ability of colon cancer cells. PMID: 19565570
- TSLL2 is expressed at the cell-cell attachment sites in the renal tubules, the transitional epithelia of the bladder, and the glandular epithelia of the prostate, and is a tumor-suppressor candidate in prostate cancer. PMID: 16261159
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亞細胞定位：Membrane; Single-pass type I membrane protein.
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蛋白家族：Nectin family
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組織特異性：Expressed in brain, prostate, brain, kidney and some other organs.
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數(shù)據(jù)庫鏈接：
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