BCL2L13 Antibody
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中文名稱：BCL2L13兔多克隆抗體
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貨號：CSB-PA002617GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：BCL2L13; MIL1; CD003; Bcl-2-like protein 13; Bcl2-L-13; Bcl-rambo; Protein Mil1
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human BCL2L13
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC,IF
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：May promote the activation of caspase-3 and apoptosis.
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基因功能參考文獻：
- Ectopically expressed in Drosophila Bcl-rambo localizes to mitochondria, induces apoptosis and atrophied wing, split thorax, and rough eye phenotypes. PMID: 27348811
- This study showed that Bcl-2-like protein 13 (Bcl2-L-13) induces mitochondrial fragmentation and mitophagy in mammalian cells. PMID: 26146385
- Bcl2L13 binds to proapoptotic ceramide synthases 2 (CerS2) and 6 (CerS6) via a unique C-terminal 250-aa sequence located between its Bcl-2 homology and membrane anchor domains and blocks homo- and heteromeric CerS2/6 complex formation and activity. PMID: 24706805
- Bcl-rambo is a pro-apoptotic member of the Bcl-2 family, inducing the permeability transition via interaction with the adenine nucleotide translocator (ANT). PMID: 22921587
- Our data support the speculation that the Alu element insertion during the splicing process may play an important role in the generation of protein diversity in primate cells by a yet uncharacterized mechanism PMID: 12527362
- SidF contributes to apoptosis resistance in L. pneumophila-infected cells by specifically interacting with and neutralizing the effects of BNIP3 and Bcl-rambo, two proapoptotic members of Bcl2 protein family. PMID: 17360363
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亞細胞定位：[Isoform 2]: Mitochondrion membrane; Single-pass membrane protein. Nucleus.; [Isoform 1]: Nucleus.
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蛋白家族：Bcl-2 family
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組織特異性：Ubiquitous, with the highest levels of expression in heart, placenta and pancreas.
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數據庫鏈接：
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