ANGPT4 Antibody
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中文名稱：ANGPT4兔多克隆抗體
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貨號：CSB-PA584378
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA584378(ANGPT4 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA584378(ANGPT4 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200) -
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human right lung tissue, Human left lung cancer tissue, Primary antibody: CSB-PA584378(ANGPT4 Antibody) at dilution 1/480, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：AGP4 antibody; ANG-3 antibody; ANG-4 antibody; ANG3 antibody; ANG4 antibody; Angiopoietin 3 antibody; Angiopoietin 4 antibody; Angiopoietin-3 antibody; Angiopoietin-4 antibody; ANGP4_HUMAN antibody; ANGPT4 antibody; dJ824F16.2 (angiopoietin 4) antibody; MGC138181 antibody; MGC138183 antibody; OTTHUMP00000029947 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Synthetic peptide of Human ANGPT4
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:10000 WB 1:200-1:1000 IHC 1:100-1:300 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis.
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基因功能參考文獻：
- Ang-4 also promoted survival of LECs. Thus, blocking Ang-4 may prune the draining lymphatic vasculature and decrease interstitial fluid pressure (IFP) by reducing vascular permeability. PMID: 25977256
- acute-phase protein A1AT is a physiological regulator of angptl4, another acute-phase protein. PMID: 24760148
- Angptl4 is a glucocorticoid-responsive mediator of fasting-induced intracellular lipolysis and stimulates cAMP signaling in adipocytes PMID: 22267746
- In tumor cells, only Ang-4 expression has prognostic impact in NSCLC. In NSCLC tumor stroma, Ang-4 and Ang-2 are independently associated with survival. PMID: 21603628
- Linkage to 20p13 including the ANGPT4 gene in families with mixed Alzheimer disease and vascular dementia is reported. PMID: 20596041
- Results establish the novel effects of Ang-4 on tumor angiogenesis and GBM progression and suggest that this pro-GBM effect of Ang-4 is mediated by promoting tumor angiogenesis and activating Erk1/2 kinase in GBM cells. PMID: 20823154
- the angiopoietin/Tie-2 system may participate in the angiogenic response to hypoxia in renal tissues and in tumor angiogenesis in renal carcinoma. PMID: 15198927
- Recombinant Ang4 formed disulfide-linked dimers. Ang4 produces corneal angiogenesis extending from the limbus across the mouse cornea in vivo. Ang4 is an agonist of Tie2. PMID: 15284220
- angiopoietin-4 inhibits angiogenesis and reduces interstitial fluid pressure PMID: 16790085
- Results describe the expression of angiopoietin-1, 2 and 4 and Tie-1 and 2 in gastrointestinal stromal tumors, leiomyomas and schwannomas. PMID: 17724803
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亞細胞定位：Secreted.
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組織特異性：Highly expressed in the lung with much lower levels found in other tissues.
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數據庫鏈接：
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