ALDH1B1 Antibody
-
中文名稱：ALDH1B1兔多克隆抗體
-
貨號：CSB-PA001568ESR1HU
-
規格：￥440
-
圖片：
-
Western blot
All lanes: Aldehyde dehydrogenase X, mitochondrial antibody at 4μg/ml
Lane 1: Hela whole cell lysate
Lane 2: Rat brain tissue
Lane 3: HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 57 kDa
Observed band size: 57 kDa -
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA001568ESR1HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA001568ESR1HU at dilution of 1:100
-
-
其他：
產品詳情
-
產品名稱：Rabbit anti-Homo sapiens (Human) ALDH1B1 Polyclonal antibody
-
Uniprot No.：
-
基因名：ALDH1B1
-
別名：Acetaldehyde dehydrogenase 5 antibody; AL1B1_HUMAN antibody; Aldehyde dehydrogenase 1 family; member B1 antibody; Aldehyde dehydrogenase 1B1 antibody; Aldehyde dehydrogenase 5 antibody; Aldehyde dehydrogenase family 1 member B1 antibody; Aldehyde dehydrogenase X antibody; Aldehyde dehydrogenase X mitochondrial antibody; ALDH class 2 antibody; Aldh1b1 antibody; ALDH5 antibody; ALDHX antibody; MGC2230 antibody; Mitochondrial aldehyde dehydrogenase X antibody; mitochondrial antibody; OTTHUMP00000021399 antibody
-
宿主：Rabbit
-
反應種屬：Human, Rat
-
免疫原：Recombinant Human Aldehyde dehydrogenase X, mitochondrial protein (278-517AA)
-
免疫原種屬：Homo sapiens (Human)
-
標記方式：Non-conjugated
-
克隆類型：Polyclonal
-
抗體亞型：IgG
-
純化方式：Antigen Affinity Purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
-
產品提供形式：Liquid
-
應用范圍：ELISA, WB, IHC
-
推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:20-1:200 -
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
功能：ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation.
-
基因功能參考文獻：
- These results suggest that ALDH1B1 is a novel human colorectal cancer biomarker PMID: 28881356
- The aims of this study were: (i) to use bioinformatic techniques to characterize the possible effects of selected variants in ALDH1B1 on protein structure and function; and, (ii) to genotype three missense and one stop-gain, protein-altering, non-synonymous single nucleotide polymorphisms in 1478 alcohol dependent cases and 1254 controls of matched British and Irish ancestry. PMID: 28594837
- ALDH1B1 is expressed at very high levels in human pancreatic cancer, and it contributes to proliferation in these tumor cells. PMID: 26566217
- High expression of ALDH1A2 and ALDH1B1 mRNA was found to be significantly correlated to worser survival in all NSCLC patients. PMID: 26366059
- Data show that ALDH1B1 may promote colon cancer tumorigenesis by modulating the Wnt/beta-catenin, Notch and PI3K/Akt signaling pathways. PMID: 25950950
- ALDH1B1 metabolizes nitroglycerin and all-trans-retinaldehyde. One of the three human polymorphisms, ALDH1B1*2, is catalytically inactive, likely due to poor NAD(+) binding. PMID: 25413692
- ALDH1B1 SNPs play a role in shaping the alcohol drinking patterns among the Inuit in Greenland. PMID: 25311581
- ALDH1 is indicative of stemness and is a biomarker marker in colon cancer. PMID: 24953984
- ALDH1B1 is more profoundly expressed in the adenocarcinomas examined in this study relative to ALDH1A1 and that ALDH1B1 is dramatically upregulated in human colonic adenocarcinoma, making it a potential biomarker for human colon cancer. PMID: 21216231
- An ALDHX model based on the crystal structure of human ALDH2, reveals similarities with the previously described ALDH structures. Analyses indicate a close structural and functional relationship between the two isoenzymes of human origin PMID: 20955166
- a common SNP encoding ALDH1b1 (rs2228093) was found to be significantly associated with alcohol-induced hypersensitivity. PMID: 20205700
- ALDH1b1 ala69val was associated with diastolic blood pressure in a Caucasian population sample PMID: 18782342
顯示更多
收起更多
-
亞細胞定位：Mitochondrion matrix.
-
蛋白家族：Aldehyde dehydrogenase family
-
組織特異性：Liver, testis and to a lesser extent in brain.
-
數據庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
