ADH7 Antibody
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中文名稱：ADH7兔多克隆抗體
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貨號：CSB-PA098332
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規格：￥2024
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圖片：
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Western blot analysis of extracts from COS cells, using ADH7 antibody.
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) ADH7 Polyclonal antibody
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Uniprot No.：
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基因名：ADH7
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宿主：Rabbit
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反應種屬：Human
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免疫原：Synthesized peptide derived from internal of Human ADH7.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Polyclonal
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:3000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Catalyzes the NAD-dependent oxidation of all-trans-retinol, alcohol, and omega-hydroxy fatty acids and their derivatives. Oxidizes preferentially all trans-retinol, all-trans-4-hydroxyretinol, 9-cis-retinol, 2-hexenol, and long chain omega-hydroxy fatty acids such as juniperic acid. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and aldehydes and their derivatives. Reduces preferentially all trans-retinal, all-trans-4-oxoretinal and hexanal. Catalyzes in the oxidative direction with higher efficiency. Therefore may participate in retinoid metabolism, fatty acid omega-oxidation, and elimination of cytotoxic aldehydes produced by lipid peroxidation.
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基因功能參考文獻：
- These results suggest that variants near ADH7 may play a role in protection from alcohol dependence in this Mexican American cohort. PMID: 25527893
- Transcriptional regulatory elements of ADH7 were identified that effect gene expression. PMID: 24512552
- common ADH1-7 variants conferred risk for both schizophrenia in African-Americans and autism in European-Americans. PMID: 23468174
- The rs1573496 (ADH7) polymorphism was not associated with colorectal cancer risk overall in Western-European populations. However, the relationship between alcohol and colorectal cancer risk might be modulated by the rs1573496 (ADH7) polymorphism. PMID: 23149980
- The current results support the ADH7 A92G SNP as a marker for the risk of SCCHN in non-Hispanic white populations. PMID: 20336794
- An association between age at onset of regular alcohol use and a SNP just upstream of ADH7 (rs2654849, p = .003) was observed. PMID: 20158305
- ADH7 gene polymorphisms are associated with upper aerodigestive tract cancers. PMID: 19861527
- the ADH7 variation may contribute to the genetic component of variation in personality traits, with the risk for SD and personality traits being partially shared. PMID: 17918242
- A recombinational hotspot within intron 7 of the ADH7 gene were seen using 25 SNPs; haplotypes associated with inter-individual variation in the early stages of alcohol metabolism were identified. PMID: 17921519
- Changes in the activity of class IV ADH in the sera of patients with gastric cancer seems to be caused by release of the isoenzyme from cancer cells. PMID: 18231859
- Single Nucleotide Polymorphism in ADH7 gene is associated with upper aerodigestive cancer. PMID: 18500343
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亞細胞定位：Cytoplasm.
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蛋白家族：Zinc-containing alcohol dehydrogenase family, Class-IV subfamily
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組織特異性：Preferentially expressed in stomach.
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數據庫鏈接：
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