HDAC4 Monoclonal Antibody
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中文名稱：HDAC4鼠單克隆抗體
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貨號(hào)：CSB-MA970585
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規(guī)格：￥2621
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其他：
產(chǎn)品詳情
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產(chǎn)品描述：HDAC4單克隆抗體（CUSABIO貨號(hào)：CSB-MA970585）是針對(duì)組蛋白去乙酰化酶4（HDAC4）研發(fā)的高特異性科研試劑，適用于人、小鼠、大鼠樣本的檢測(cè)。HDAC4作為表觀遺傳調(diào)控關(guān)鍵酶，通過(guò)介導(dǎo)組蛋白去乙?；揎梾⑴c基因表達(dá)調(diào)控、細(xì)胞分化等重要生物學(xué)過(guò)程，其異常表達(dá)與神經(jīng)發(fā)育、代謝性疾病及腫瘤發(fā)生等病理機(jī)制密切相關(guān)。本產(chǎn)品采用雜交瘤技術(shù)制備，在ELISA、Western Blot及免疫細(xì)胞化學(xué)（ICC）等實(shí)驗(yàn)中表現(xiàn)優(yōu)異，能有效識(shí)別內(nèi)源性HDAC4蛋白?？贵w經(jīng)嚴(yán)格驗(yàn)證具備良好種屬兼容性，適用于探究HDAC4在神經(jīng)退行性疾病模型、癌癥細(xì)胞系以及發(fā)育生物學(xué)研究中的動(dòng)態(tài)表達(dá)與亞細(xì)胞定位，為表觀遺傳學(xué)、細(xì)胞周期調(diào)控及疾病分子機(jī)制研究提供可靠工具。該抗體特別適用于蛋白質(zhì)相互作用研究、信號(hào)通路分析及靶向藥物開(kāi)發(fā)等前沿領(lǐng)域，是開(kāi)展HDAC家族功能研究的優(yōu)選試劑。
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別名：histone deacetylase 4 histone deacetylase A
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宿主：Mouse
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Recombinant fragment, corresponding to amino acids 16aa-225aa of Human HDAC4(N-terminus).
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Monoclonal
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抗體亞型：IgG2a
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純化方式：Antigen Affinity Purified
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克隆號(hào)：24B10
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濃度：It differs from different batches. Please contact us to confirm it.
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產(chǎn)品提供形式：Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
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應(yīng)用范圍：ELISA,WB,ICC
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:5000 ICC 1:50-1:200 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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