RPS6KB1
Ribosomal protein S6 kinase beta-1 is a protein in humans that is encoded by RPS6KB1 gene. Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by repressing the pro-apoptotic function of BAD. Under conditions of nutrient depletion, the inactive form associates with the EIF3 translation initiation complex. Upon mitogenic stimulation, phosphorylation by the mammalian target of rapamycin complex 1 (mTORC1) leads to dissociation from the EIF3 complex and activation. The active form then phosphorylates and activates several substrates in the pre-initiation complex, including the EIF2B complex and the cap-binding complex component EIF4B.
RPS6KB1 Antibodies
RPS6KB1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA020470GA01HU | RPS6KB1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA075982 | Phospho-RPS6KB1 (Thr421) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA177270 | Phospho-RPS6KB1 (Ser411) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA108937 | Phospho-RPS6KB1 (Ser424) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA204361 | RPS6KB1 (Ab-389) Antibody | Human,Mouse,Rat | ELISA,WB,IF |
| CSB-PA268989 | RPS6KB1 (Ab-421) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA573095 | RPS6KB1 (Ab-411) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA090473 | RPS6KB1 (Ab-424) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA908216 | Phospho-RPS6KB1 (Thr229) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA061411 | Phospho-RPS6KB1 (Ser371) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA073005 | Phospho-RPS6KB1 (Thr389/412) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA996769 | RPS6KB1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA000604 | Phospho-RPS6KB1 (S447) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA000605 | Phospho-RPS6KB1 (T229) Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA003686 | RPS6KB1 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA003688 | RPS6KB1 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA040258 | Phospho-RPS6KB1 (S434) Antibody | Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
| CSB-PA040259 | Phospho-RPS6KB1 (T421) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA040260 | Phospho-RPS6KB1 (T444) Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA040261 | Phospho-RPS6KB1 (S371) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA040262 | Phospho-RPS6KB1 (T412) Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA040263 | Phospho-RPS6KB1 (S418) Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA040264 | Phospho-RPS6KB1 (S427) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA040265 | RPS6KB1 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA040266 | RPS6KB1 Antibody | Human,Mouse,Rat | IHC, ELISA |
| CSB-PA040267 | RPS6KB1 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA080221 | RPS6KB1 Antibody | Human,Mouse,Rat | WB, IHC |
| CSB-PA080222 | RPS6KB1 Antibody | Mouse,Rat | WB,IHC |
| CSB-PA620256 | RPS6KB1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA241902 | RPS6KB1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA020470LA01HU | RPS6KB1 Antibody | Human | ELISA, IF, IP |
| CSB-PA020470LB01HU | RPS6KB1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA020470LC01HU | RPS6KB1 Antibody, FITC conjugated | Human | |
| CSB-PA020470LD01HU | RPS6KB1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA020470A421phHU | Phospho-RPS6KB1 (T421+S424) Recombinant Monoclonal Antibody | Human | ELISA, WB, IF, IP |
| CSB-RA779090A0HU | RPS6KB1 Recombinant Monoclonal Antibody | Human, Mouse | ELISA, WB |
| CSB-RA299200A0HU | RPS6KB1 Recombinant Monoclonal Antibody | Human | ELISA, IF |
RPS6KB1 Proteins
RPS6KB1 Proteins for Oryctolagus cuniculus (Rabbit)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP020470RB CSB-EP020470RB CSB-BP020470RB CSB-MP020470RB CSB-EP020470RB-B |
Recombinant Rabbit Ribosomal protein S6 kinase beta-1 (RPS6KB1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RPS6KB1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP020470HU CSB-EP020470HU CSB-BP020470HU CSB-MP020470HU CSB-EP020470HU-B |
Recombinant Human Ribosomal protein S6 kinase beta-1 (RPS6KB1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RPS6KB1 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP020470RA CSB-EP020470RA CSB-BP020470RA CSB-MP020470RA CSB-EP020470RA-B |
Recombinant Rat Ribosomal protein S6 kinase beta-1 (Rps6kb1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RPS6KB1 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP740885BO CSB-EP740885BO CSB-BP740885BO CSB-MP740885BO CSB-EP740885BO-B |
Recombinant Bovine Ribosomal protein S6 kinase beta-1 (RPS6KB1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RPS6KB1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP804395MO CSB-EP804395MO CSB-BP804395MO CSB-MP804395MO CSB-EP804395MO-B |
Recombinant Mouse Ribosomal protein S6 kinase beta-1 (Rps6kb1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
