KREMEN1
Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. In the absence of DKK1, potentiates Wnt-beta-catenin signaling by maintaining LRP5 or LRP6 at the cell membrane. Can trigger apoptosis in a Wnt-independent manner and this apoptotic activity is inhibited upon binding of the ligand DKK1. Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning and can also negatively regulate bone formation. Modulates cell fate decisions in the developing cochlea with an inhibitory role in hair cell fate specification.
KREMEN1 Antibodies
KREMEN1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA850397ESR2HU | KREMEN1 Antibody | Human | ELISA, IHC |
KREMEN1 Proteins
KREMEN1 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP846071RA CSB-EP846071RA CSB-BP846071RA CSB-MP846071RA CSB-EP846071RA-B |
Recombinant Rat Kremen protein 1 (Kremen1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KREMEN1 Proteins for Xenopus laevis (African clawed frog)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP849554XBE CSB-EP849554XBE CSB-BP849554XBE CSB-MP849554XBE CSB-EP849554XBE-B |
Recombinant Xenopus laevis Kremen protein 1 (kremen1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KREMEN1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP850397HU CSB-EP850397HU CSB-BP850397HU CSB-MP850397HU CSB-EP850397HU-B |
Recombinant Human Kremen protein 1 (KREMEN1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KREMEN1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP860404MO CSB-EP860404MO CSB-BP860404MO CSB-MP860404MO CSB-EP860404MO-B |
Recombinant Mouse Kremen protein 1 (Kremen1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
