Recombinant Rat Activator of apoptosis harakiri (Hrk), partial

中文名稱：

大鼠Hrk重組蛋白
貨號(hào)：

CSB-YP010741RA1
規(guī)格：
來源：

Yeast
其他：

中文名稱：

大鼠Hrk重組蛋白
貨號(hào)：

CSB-EP010741RA1
規(guī)格：
來源：

E.coli
其他：

中文名稱：

大鼠Hrk重組蛋白
貨號(hào)：

CSB-EP010741RA1-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Hrk重組蛋白
貨號(hào)：

CSB-BP010741RA1
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Hrk重組蛋白
貨號(hào)：

CSB-MP010741RA1
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價(jià)
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產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Hrk
Uniprot No.：

P62817
別名：

Hrk; Bid3; Dp5; Activator of apoptosis harakiri; BH3-interacting domain-containing protein 3; Neuronal death protein DP5
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

功能：

Promotes apoptosis.
基因功能參考文獻(xiàn)：
1. BH3 peptide has a role in releasing cytochrome c in rat brain mitochondria PMID: 12700636
2. dp5 is a target gene of c-Jun and plays a critical role in potassium deprivation-induced apoptosis in cerebellar granule neurons. PMID: 17428807
3. Bcl-2 regulates an essential pool of mitochondrial GSH and this regulation may depend upon Bcl-2 directly interacting with GSH via the BH3 groove PMID: 17690097
4. identification of a conserved ATF site in the dp5 promoter that binds c-Jun and ATF2, which is critical for dp5 promoter induction after NGF withdrawal. PMID: 19304750
5. The inactivation of hrk protein protects -cells from IL-1beta+IFN-gamma and chemical Endoplasmic Reticulum stress-mediated cell death. PMID: 19629134
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亞細(xì)胞定位：

Membrane; Single-pass membrane protein. Mitochondrion.
數(shù)據(jù)庫鏈接：

KEGG: rno:117271

UniGene: Rn.233779