STX16 Antibody
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中文名稱：STX16兔多克隆抗體
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貨號：CSB-PA560536
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規(guī)格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA560536(STX16 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA560536(STX16 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200) -
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hela cells, hepg2 cells, Primary antibody: CSB-PA560536(STX16 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
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其他：
產品詳情
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Uniprot No.：
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基因名：STX16
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別名：STX16; Syntaxin-16; Syn16
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Fusion protein of Human STX16
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:5000 WB 1:500-1:2000 IHC 1:25-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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功能：SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.
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基因功能參考文獻：
- we here present a patient with PHP1b caused by a recurrent STX16 deletion, presenting with macrosomia, early onset obesity, and macrocephaly without other AHO symptoms. we reemphasize STX16 deletions and PHP1b as a rare cause for early onset obesity and macrosomia. PMID: 27338644
- STX16 microdeletion was identified in male monozygotic twins (with pseudohypoparathyroidism type 1B leading to growth hormone deficiency) and mother/grandmother (not father/grandfather or sister [their triplet with separate placenta]). [CASE STUDY] PMID: 25843330
- syntaxin 16 is a key regulator of cytokinesis. PMID: 24109596
- A patient with familial pseudohypoparathyroidism type Ib and his asymptomatic brother were found to have methylation defect at GNAS (guanine nucleotide-binding protein G) and microdeletion involving exons 4-6 of neighboring gene STX16. [CASE REPORT] PMID: 23095209
- De novo 3-kb STX16 deletions, reported only once previously, are infrequent but should be excluded in all cases of Pseudohypoparathyroidism-Ib, even when the family history is negative for an inherited form of this disorder. PMID: 23087324
- Results suggest that STX16 mediates recycling of CFTR and constitutes an important component of CFTR trafficking machinery in intestinal epithelial cells. PMID: 20826815
- the region of overlap between the two microdeletions likely harbors a cis-acting imprinting control element that is necessary for establishing and methylation at GNAS exon A/B, thus allowing normal G alpha(s) expression in the proximal renal tubules. I PMID: 15800843
- function of syntaxin 16 was specifically required for, and restricted to, the retrograde pathway PMID: 17389686
- Syntaxin 16 may thus play a role in neurite outgrowth and perhaps other specific dendritic anterograde/retrograde traffic. PMID: 17852734
- phosphorylation of RASSF1A by Aurora B is required for the recruitment of Syntaxin16 PMID: 19887622
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相關疾病：Pseudohypoparathyroidism 1B (PHP1B)
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亞細胞定位：Golgi apparatus membrane; Single-pass type IV membrane protein.; [Isoform C]: Cytoplasm.
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蛋白家族：Syntaxin family
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組織特異性：Ubiquitous.
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數據庫鏈接：
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